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Can We Produce Heparin/Heparan Sulfate Biomimetics Using “Mother-Nature” as the Gold Standard?

Heparan sulfate (HS) and heparin are glycosaminoglycans (GAGs) that are heterogeneous in nature, not only due to differing disaccharide combinations, but also their sulfate modifications. HS is well known for its interactions with various growth factors and cytokines; and heparin for its clinical us...

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Detalles Bibliográficos
Autores principales: Farrugia, Brooke L., Lord, Megan S., Melrose, James, Whitelock, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272578/
https://www.ncbi.nlm.nih.gov/pubmed/25751786
http://dx.doi.org/10.3390/molecules20034254