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Development of Orally Active Thrombin Inhibitors for the Treatment of Thrombotic Disorder Diseases

Thrombotic disorders represent the major share of the various cardiovascular diseases, and significant progress has been made in the development of synthetic thrombin inhibitors as new anticoagulants. In addition to the development of highly potent and selective inhibitors with improved safety and s...

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Detalles Bibliográficos
Autores principales: He, Li-Wei, Dai, Wei-Chen, Li, Nian-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272601/
https://www.ncbi.nlm.nih.gov/pubmed/26083038
http://dx.doi.org/10.3390/molecules200611046