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Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu

Macromolecular crowding is known to affect protein folding, binding of small molecules, interaction with nucleic acids, enzymatic activity, protein-protein interactions, and protein aggregation. Although for a long time it was believed that the major mechanism of the action of crowded environments o...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Irina M., Zaslavsky, Boris Y., Breydo, Leonid, Turoverov, Konstantin K., Uversky, Vladimir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272634/
https://www.ncbi.nlm.nih.gov/pubmed/25594347
http://dx.doi.org/10.3390/molecules20011377