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Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu
Macromolecular crowding is known to affect protein folding, binding of small molecules, interaction with nucleic acids, enzymatic activity, protein-protein interactions, and protein aggregation. Although for a long time it was believed that the major mechanism of the action of crowded environments o...
Autores principales: | Kuznetsova, Irina M., Zaslavsky, Boris Y., Breydo, Leonid, Turoverov, Konstantin K., Uversky, Vladimir N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272634/ https://www.ncbi.nlm.nih.gov/pubmed/25594347 http://dx.doi.org/10.3390/molecules20011377 |
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