An Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Catalyzed by a Novel Brønsted Acidic Ionic Liquid under Solvent-Free Conditions

We report here an efficient and green method for Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea catalyzed by Brønsted acidic ionic liquid [Btto][p-TSA] under solvent-free conditions. Compared to the classical Biginelli reaction conditions, the present method has the...

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Detalles Bibliográficos
Autores principales: Zhang, Yonghong, Wang, Bin, Zhang, Xiaomei, Huang, Jianbin, Liu, Chenjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272654/
https://www.ncbi.nlm.nih.gov/pubmed/25730389
http://dx.doi.org/10.3390/molecules20033811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272654/
https://www.ncbi.nlm.nih.gov/pubmed/25730389
http://dx.doi.org/10.3390/molecules20033811

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