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Synthesis, Anti-Tumor and Anti-Angiogenic Activity Evaluations of Asiatic Acid Amino Acid Derivatives

Fifteen semi-synthetic derivatives of asiatic acid (AA) have been synthesized and evaluated for their biological activities. The successful modification of these compounds at the C-2, C-3, C-23 and C-28 positions was confirmed using NMR, MS and IR spectra. Further, their anti-tumor effects were eval...

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Detalles Bibliográficos
Autores principales: Jing, Yue, Wang, Gang, Ge, Ying, Xu, Minjie, Gong, Zhunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272655/
https://www.ncbi.nlm.nih.gov/pubmed/25905607
http://dx.doi.org/10.3390/molecules20047309