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Development of New 1,3-Diazaphenoxazine Derivatives (ThioG-Grasp) to Covalently Capture 8-Thioguanosine

The derivatives of 8-thioguanosine are thought to be included in the signal transduction system related to 8-nitroguanosine. In this study, we attempted to develop new 1,3-diazaphenoxazine (G-clamp) derivatives to covalently capture 8-thioguanosine (thioG-grasp). It was expected that the chlorine at...

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Detalles Bibliográficos
Autores principales: Fuchi, Yasufumi, Obayashi, Hideto, Sasaki, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272678/
https://www.ncbi.nlm.nih.gov/pubmed/25584836
http://dx.doi.org/10.3390/molecules20011078