Formulations, Hemolytic and Pharmacokinetic Studies on Saikosaponin a and Saikosaponin d Compound Liposomes

The aim of this study was to develop and optimise a saikosaponin a and saikosaponin d compound liposome (SSa-SSd-Lip) formulation with reduced hemolysis and enhanced bioavailability. A screening experiment was done with Plackett–Burman design, and response surface methodology of five factors (EPC/SS...

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Detalles Bibliográficos
Autores principales: Zhang, Guo-Song, Hu, Peng-Yi, Li, Dong-Xun, He, Ming-Zhen, Rao, Xiao-Yong, Luo, Xiao-Jian, Wang, Yue-Sheng, Wang, Yu-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272718/
https://www.ncbi.nlm.nih.gov/pubmed/25854754
http://dx.doi.org/10.3390/molecules20045889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272718/
https://www.ncbi.nlm.nih.gov/pubmed/25854754
http://dx.doi.org/10.3390/molecules20045889

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