Cargando…

Development of Sulfadiazine-Decorated PLGA Nanoparticles Loaded with 5-Fluorouracil and Cell Viability

The aim of this work was to synthesize sulfadiazine-poly(lactide-co-glycolide) (SUL-PLGA) nanoparticles (NPs) for the efficient delivery of 5-fluorouracil to cancer cells. The SUL-PLGA conjugation was assessed using FTIR, (1)H-NMR, (13)C-NMR, elemental analysis and TG and DTA analysis. The SUL-PLGA...

Descripción completa

Detalles Bibliográficos
Autores principales: Guimarães, Pedro Pires Goulart, Oliveira, Sheila Rodrigues, de Castro Rodrigues, Gabrielle, Gontijo, Savio Morato Lacerda, Lula, Ivana Silva, Cortés, Maria Esperanza, Denadai, Ângelo Márcio Leite, Sinisterra, Rubén Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272719/
https://www.ncbi.nlm.nih.gov/pubmed/25580685
http://dx.doi.org/10.3390/molecules20010879