Chelation-Assisted Substrate-Controlled Asymmetric Lithiation-Allylboration of Chiral Carbamate 1,2,4-Butanetriol Acetonide

The lithiation of 2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl diisopropylcarbamate (1) is achieved freely by sec-butyllithium in diethylether with high lk-diastereoselectivity: the bicyclic chelate complexes 3a and 3b are reacted with electrophiles to form optically active precursors 4a and 4b with >...

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Detalles Bibliográficos
Autores principales: Mahmood, Adeem, Alkhathlan, Hamad Z., Parvez, Saima, Khan, Merajuddin, Shahzad, Sohail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272734/
https://www.ncbi.nlm.nih.gov/pubmed/26029858
http://dx.doi.org/10.3390/molecules20069890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272734/
https://www.ncbi.nlm.nih.gov/pubmed/26029858
http://dx.doi.org/10.3390/molecules20069890

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