4-[(18)F]Fluorophenylpiperazines by Improved Hartwig-Buchwald N-Arylation of 4-[(18)F]fluoroiodobenzene, Formed via Hypervalent λ(3)-Iodane Precursors: Application to Build-Up of the Dopamine D(4) Ligand [(18)F]FAUC 316

Substituted phenylpiperazines are often neuropharmacologically active compounds and in many cases are essential pharmacophores of neuroligands for different receptors such as D(2)-like dopaminergic, serotoninergic and other receptors. Nucleophilic, no-carrier-added (n.c.a.) (18)F-labelling of these...

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Detalles Bibliográficos
Autores principales: Kügler, Fabian, Ermert, Johannes, Kaufholz, Peter, Coenen, Heinz H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272738/
https://www.ncbi.nlm.nih.gov/pubmed/25558857
http://dx.doi.org/10.3390/molecules20010470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272738/
https://www.ncbi.nlm.nih.gov/pubmed/25558857
http://dx.doi.org/10.3390/molecules20010470

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