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Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787

Glutaredoxin (Grx), peroxiredoxin (Prx), and thioredoxin (Trx) are redoxin family proteins that catalyze different types of chemical reactions that impact cell growth and survival through functionally distinct intracellular pathways. Much research is focused on understanding the roles of these redox...

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Detalles Bibliográficos
Autores principales: Parker, Aulma R., Petluru, Pavankumar N., Nienaber, Vicki L., Badger, John, Leverett, Betsy D., Jair, Kamwing, Sridhar, Vandana, Logan, Cheyenne, Ayala, Philippe Y., Kochat, Harry, Hausheer, Frederick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272748/
https://www.ncbi.nlm.nih.gov/pubmed/25793542
http://dx.doi.org/10.3390/molecules20034928