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Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives

The reaction of 1-adamantyl isothiocyanate 4 with the various cyclic secondary amines yielded the corresponding N-(1-adamantyl)carbothioamides 5a–e, 6, 7, 8a–c and 9. Similarly, the reaction of 4 with piperazine and trans-2,5-dimethylpiperazine in 2:1 molar ratio yielded the corresponding N,N'-...

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Detalles Bibliográficos
Autores principales: Al-Abdullah, Ebtehal S., Al-Tuwaijri, Hanaa M., Hassan, Hanan M., Al-Alshaikh, Monirah A., Habib, Elsayed E., El-Emam, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272754/
https://www.ncbi.nlm.nih.gov/pubmed/25955889
http://dx.doi.org/10.3390/molecules20058125