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Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

Assessing the human placental barrier permeability of drugs is very important to guarantee drug safety during pregnancy. Quantitative structure–activity relationship (QSAR) method was used as an effective assessing tool for the placental transfer study of drugs, while in vitro human placental perfus...

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Detalles Bibliográficos
Autores principales: Zhang, Yong-Hong, Xia, Zhi-Ning, Yan, Li, Liu, Shu-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272791/
https://www.ncbi.nlm.nih.gov/pubmed/25961165
http://dx.doi.org/10.3390/molecules20058270