Synthesis and Evaluation of New 1,5-Diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole Derivatives as Potential Antidepressant Agents

In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a–s were synthesized and evaluated for their antidepressant-like activity by tail suspension test (TST) and modified forced swimming test (MFST). The effects of the compounds on spontaneous locomotor activity were also...

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Detalles Bibliográficos
Autores principales: Özdemir, Ahmet, Altıntop, Mehlika Dilek, Kaplancıklı, Zafer Asım, Can, Özgür Devrim, Özkay, Ümide Demir, Turan-Zitouni, Gülhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272793/
https://www.ncbi.nlm.nih.gov/pubmed/25658142
http://dx.doi.org/10.3390/molecules20022668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272793/
https://www.ncbi.nlm.nih.gov/pubmed/25658142
http://dx.doi.org/10.3390/molecules20022668

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