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Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations

Toll-Like Receptors (TLR) are a large family of proteins involved in the immune system response. Both the activation and the inhibition of these receptors can have positive effects on several diseases, including viral pathologies and cancer, therefore prompting the development of new compounds. In o...

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Detalles Bibliográficos
Autores principales: Gentile, Francesco, Deriu, Marco A., Licandro, Ginevra, Prunotto, Alessio, Danani, Andrea, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272798/
https://www.ncbi.nlm.nih.gov/pubmed/26007168
http://dx.doi.org/10.3390/molecules20058316