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Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations
Toll-Like Receptors (TLR) are a large family of proteins involved in the immune system response. Both the activation and the inhibition of these receptors can have positive effects on several diseases, including viral pathologies and cancer, therefore prompting the development of new compounds. In o...
Autores principales: | Gentile, Francesco, Deriu, Marco A., Licandro, Ginevra, Prunotto, Alessio, Danani, Andrea, Tuszynski, Jack A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272798/ https://www.ncbi.nlm.nih.gov/pubmed/26007168 http://dx.doi.org/10.3390/molecules20058316 |
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