In Silico Affinity Profiling of Neuroactive Polyphenols for Post-Traumatic Calpain Inactivation: A Molecular Docking and Atomistic Simulation Sensitivity Analysis

Calcium-activated nonlysosomal neutral proteases, calpains, are believed to be early mediators of neuronal damage associated with neuron death and axonal degeneration after traumatic neural injuries. In this study, a library of biologically active small molecular weight calpain inhibitors was used f...

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Detalles Bibliográficos
Autores principales: Kumar, Pradeep, Choonara, Yahya E., Pillay, Viness
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272800/
https://www.ncbi.nlm.nih.gov/pubmed/25546626
http://dx.doi.org/10.3390/molecules20010135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272800/
https://www.ncbi.nlm.nih.gov/pubmed/25546626
http://dx.doi.org/10.3390/molecules20010135

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