Determination of the Primary Molecular Target of 1,2,4-Triazole-Ciprofloxacin Hybrids

We have synthesized and examined the antibacterial activity, toxicity and affinity towards bacterial type II topoisomerases of a series of 1,2,4-triazole-ciprofloxacin hybrids. A number of these compounds displayed enhanced activity against Gram-positive and Gram-negative bacteria when compared to c...

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Detalles Bibliográficos
Autores principales: Plech, Tomasz, Kaproń, Barbara, Paneth, Agata, Kosikowska, Urszula, Malm, Anna, Strzelczyk, Aleksandra, Stączek, Paweł, Świątek, Łukasz, Rajtar, Barbara, Polz-Dacewicz, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272816/
https://www.ncbi.nlm.nih.gov/pubmed/25859782
http://dx.doi.org/10.3390/molecules20046254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272816/
https://www.ncbi.nlm.nih.gov/pubmed/25859782
http://dx.doi.org/10.3390/molecules20046254

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