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Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus

The haemagglutinin (HA) glycan binding selectivity of H1N1 influenza viruses is an important determinant for the host range of the virus and egg-adaption during vaccine production. This study integrates glycan binding data with structure-recognition models to examine the impact of the K123N, D225G a...

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Detalles Bibliográficos
Autores principales: Carbone, Vincenzo, Schneider, Elena K., Rockman, Steve, Baker, Mark, Huang, Johnny X., Ong, Chi, Cooper, Matthew A., Yuriev, Elizabeth, Li, Jian, Velkov, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272818/
https://www.ncbi.nlm.nih.gov/pubmed/26056814
http://dx.doi.org/10.3390/molecules200610415