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Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus
The haemagglutinin (HA) glycan binding selectivity of H1N1 influenza viruses is an important determinant for the host range of the virus and egg-adaption during vaccine production. This study integrates glycan binding data with structure-recognition models to examine the impact of the K123N, D225G a...
Autores principales: | Carbone, Vincenzo, Schneider, Elena K., Rockman, Steve, Baker, Mark, Huang, Johnny X., Ong, Chi, Cooper, Matthew A., Yuriev, Elizabeth, Li, Jian, Velkov, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272818/ https://www.ncbi.nlm.nih.gov/pubmed/26056814 http://dx.doi.org/10.3390/molecules200610415 |
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