Chemoenzymatic Synthesis of trans-β-Aryl-δ-hydroxy-γ-lactones and Enzymatic Kinetic Resolution of Their Racemic Mixtures

Two novel and convenient routes to obtain enantiomerically enriched trans-β-aryl-δ-hydroxy-γ-lactones 5a–d with potential antifeedant and anticancer activity were developed. In the first method starting from corresponding enantiomers of γ,δ-unsaturated esters 4a–d derived from enzymatically resolved...

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Detalles Bibliográficos
Autores principales: Skrobiszewski, Andrzej, Gładkowski, Witold, Maciejewska, Gabriela, Wawrzeńczyk, Czesław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272857/
https://www.ncbi.nlm.nih.gov/pubmed/27886108
http://dx.doi.org/10.3390/molecules21111552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272857/
https://www.ncbi.nlm.nih.gov/pubmed/27886108
http://dx.doi.org/10.3390/molecules21111552

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