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In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin: Prediction of in Vivo Dietary Supplement-Drug Interactions

Despite the widespread use of the five major xanthophylls astaxanthin, β-cryptoxanthin, canthaxanthin, lutein, and zeaxanthin as dietary supplements, there have been no studies regarding their inhibitory effects on hepatic UDP-glucuronosyltransferases (UGTs). Here, we evaluated the inhibitory potent...

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Detalles Bibliográficos
Autores principales: Zheng, Yu Fen, Min, Jee Sun, Kim, Doyun, Park, Jung Bae, Choi, Sung-Wook, Lee, Eun Seong, Na, Kun, Bae, Soo Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272861/
https://www.ncbi.nlm.nih.gov/pubmed/27529203
http://dx.doi.org/10.3390/molecules21081052