Synthesis and Evaluation of Bicyclo[3.1.0]hexane-Based UDP-Galf Analogues as Inhibitors of the Mycobacterial Galactofuranosyltransferase GlfT2

UDP-galactofuranose (UDP-Galf) is the donor substrate for both bifunctional galactofuranosyltransferases, GlfT1 and GlfT2, which are involved in the biosynthesis of mycobacterial galactan. In this paper, a group of UDP-Galf mimics were synthesized via reductive amination of a bicyclo[3.1.0]hexane-ba...

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Detalles Bibliográficos
Autores principales: Lowary, Todd L., Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272867/
https://www.ncbi.nlm.nih.gov/pubmed/27529206
http://dx.doi.org/10.3390/molecules21081053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272867/
https://www.ncbi.nlm.nih.gov/pubmed/27529206
http://dx.doi.org/10.3390/molecules21081053

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