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Antiangiogenic Effects of VH02, a Novel Urea Derivative: In Vitro and in Vivo Studies

Vascular endothelial growth factor receptor 2 (VEGFR2) is a vital target for therapeutic intervention in cancer. We have recently described a computer-based drug design for a small molecule VEGFR2 inhibitor named VH02 (1-((1-(1H-indazol-6-yl)-1H-1,2,3-triazol-4-yl)methyl)-3-(3-chloromethylphenyl)ure...

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Detalles Bibliográficos
Autores principales: Phowichit, Suwadee, Kobayashi, Miho, Fujinoya, Yuriko, Sato, Yasufumi, Sanphanya, Kingkarn, Vajragupta, Opa, Chularojmontri, Linda, Wattanapitayakul, Suvara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272876/
https://www.ncbi.nlm.nih.gov/pubmed/27657036
http://dx.doi.org/10.3390/molecules21091258