Discovery of Potent c-MET Inhibitors with New Scaffold Having Different Quinazoline, Pyridine and Tetrahydro-Pyridothienopyrimidine Headgroups

Cellular mesenchymal-epithelial transition factor (c-MET) is closely linked to human malignancies, which makes it an important target for treatment of cancer. In this study, a series of 3-methoxy-N-phenylbenzamide derivatives, N-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl) benzamide derivatives and N(1...

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Detalles Bibliográficos
Autores principales: Jiang, Yingnan, Zhang, Ke, Gao, Suyu, Wang, Guihua, Huang, Jian, Wang, Jinhui, Chen, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272887/
https://www.ncbi.nlm.nih.gov/pubmed/27187326
http://dx.doi.org/10.3390/molecules21050612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272887/
https://www.ncbi.nlm.nih.gov/pubmed/27187326
http://dx.doi.org/10.3390/molecules21050612

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