Cargando…

Synthesis, Characterization and Molecular Docking of Novel Bioactive Thiazolyl-Thiazole Derivatives as Promising Cytotoxic Antitumor Drug

Reactions of ethylidenethiocarbohydrazide with hydrazonoyl halides gave 1,3-thiazole or 1,3,4-thiadiazole derivatives according to the type of hydrazonoyl halides. Treatment of ethylidenethiosemicarbazide with hydrazonoyl halides and dimethylacetylene dicarboxylate (DMAD) afforded the corresponding...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomha, Sobhi M., Salaheldin, Taher A., Hassaneen, Huwaida M. E., Abdel-Aziz, Hassan M., Khedr, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272888/
https://www.ncbi.nlm.nih.gov/pubmed/26703554
http://dx.doi.org/10.3390/molecules21010003