Targeting Cancer Stem Cells with Novel 4-(4-Substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thiones

Novel 4-(4-substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thione derivatives (DHP 1–9) were designed, synthesized, characterized and evaluated for antitumor activity against cancer stem cells. The compounds were synthesized in one pot. Enaminones E1 an...

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Detalles Bibliográficos
Autores principales: Bhat, Mashooq Ahmad, Al-Dhfyan, Abdullah, Al-Omar, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272899/
https://www.ncbi.nlm.nih.gov/pubmed/27999374
http://dx.doi.org/10.3390/molecules21121746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272899/
https://www.ncbi.nlm.nih.gov/pubmed/27999374
http://dx.doi.org/10.3390/molecules21121746

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