Cargando…

Targeting Cancer Stem Cells with Novel 4-(4-Substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thiones

Novel 4-(4-substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thione derivatives (DHP 1–9) were designed, synthesized, characterized and evaluated for antitumor activity against cancer stem cells. The compounds were synthesized in one pot. Enaminones E1 an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhat, Mashooq Ahmad, Al-Dhfyan, Abdullah, Al-Omar, Mohamed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272899/ https://www.ncbi.nlm.nih.gov/pubmed/27999374 http://dx.doi.org/10.3390/molecules21121746

Ejemplares similares

3,4-Dihydroxyphenyl 3,4,5-trimethoxybenzoate
por: Hong, Won Ki, et al.
Publicado: (2007)

N-(3,4-Difluorophenyl)-3,4,5-trimethoxybenzamide
por: Choi, Hyeong, et al.
Publicado: (2010)

3,4,5-Trimethoxybenzohydrazidium chloride
por: Saeed, Aamer, et al.
Publicado: (2008)

5-Benzoyl-4-(4-fluorophenyl)-3,4-dihydropyrimidin-2(1H)-one
por: Kant, Rajni, et al.
Publicado: (2013)

2-Phenyl-4-(3,4,5-trimethoxybenzylidene)-1,3-oxazol-5(4H)-one
por: Sun, Yi-Feng, et al.
Publicado: (2008)

3,6-Bis(3,4,5-trimethoxyphenyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
por: Du, Hai-Tang, et al.
Publicado: (2008)

3,4,5-Trimethoxy-4′-methylbiphenyl
por: Lahtinen, Manu, et al.
Publicado: (2013)

6-(4-Methylphenyl)-3-(3,4,5-trimethoxyphenyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
por: Du, Hai-Tang, et al.
Publicado: (2008)

6-(4-Pyridyl)-3-(3,4,5-trimethoxyphenyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
por: Du, Hai-Tang, et al.
Publicado: (2008)

5-Acetyl-4-(4-methoxyphenyl)-6-methyl-3,4-dihydropyrimidine-2(1H)-thione
por: Anuradha, N., et al.
Publicado: (2009)

5-Acetyl-4-(4-chlorophenyl)-6-methyl-3,4-dihydropyrimidine-2(1H)-thione
por: Anuradha, N., et al.
Publicado: (2009)

2-Methoxy-3-[(3,4,5-trimethoxyanilino)methylidene]-3,4-dihydro-2H-1-benzopyran-4-one
por: Małecka, Magdalena, et al.
Publicado: (2009)

6-(3-Pyridyl)-3-(3,4,5-trimethoxyphenyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
por: Du, Haitang, et al.
Publicado: (2008)

4-Bromo-N-(3,4,5-trimethoxybenzylidene)aniline
por: Khalaji, Aliakbar Dehno, et al.
Publicado: (2009)

N-(4-Chlorophenyl)-3,4,5-trimethoxybenzamide
por: Saeed, Aamer, et al.
Publicado: (2008)

N′-(4-Fluorobenzylidene)-3,4,5-trimethoxybenzohydrazide
por: He, Dao-Hang, et al.
Publicado: (2008)

4-Chloro-N-(3,4,5-trimethoxybenzylidene)aniline
por: Dehno Khalaji, Aliakbar, et al.
Publicado: (2009)

N-Cyclohexyl-3,4,5-trimethoxybenzamide
por: Saeed, Aamer, et al.
Publicado: (2009)

1-[2-(3,4-Dichlorophenyl)-5-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1,3,4-oxadiazol-3-yl]ethanone
por: He, Dao-Hang, et al.
Publicado: (2008)

Tetrakis(μ-3,4-dimethoxyphenylacetato)bis[(3,4-dimethoxyphenylacetato)(1,10-phenanthroline)dysprosium(III)]
por: Liu, Jian-Feng, et al.
Publicado: (2010)

1-(3-Fluorophenyl)-4,4,6-trimethyl-3,4-dihydropyrimidine-2(1H)-thione
por: Yamin, Bohari M., et al.
Publicado: (2011)

4,4,6-Trimethyl-1-(3-methylphenyl)-3,4-dihydropyrimidine-2(1H)-thione
por: Saeed, Aamer, et al.
Publicado: (2010)

1-(3-Chlorophenyl)-4,4,6-trimethyl-3,4-dihydropyrimidine-2(1H)-thione
por: Yamin, Bohari M., et al.
Publicado: (2011)

6-(2-Methylphenyl)-3-(3,4,5-trimethoxyphenyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
por: Du, Haitang, et al.
Publicado: (2008)

5-Acetyl-4-(2-chlorophenyl)-6-methyl-3,4-dihydropyrimidine-2(1H)-thione
por: Anuradha, N., et al.
Publicado: (2009)

1-(4-Chlorophenyl)-4,4,6-trimethyl-3,4-dihydropyrimidine-2(1H)-thione
por: Saeed, Aamer, et al.
Publicado: (2010)

(E)-N′-(4-Chlorobenzylidene)-3,4,5-trimethoxybenzohydrazide
por: Wang, Yu-Min, et al.
Publicado: (2008)

N-(3-Bromophenyl)-3,4,5-trimethoxybenzamide
por: Saeed, Aamer, et al.
Publicado: (2009)

N-(3,4-Difluorophenyl)-3,4-dimethoxybenzenesulfonamide
por: You, Hyon Pil, et al.
Publicado: (2008)

2,4-Dihydroxy-N′-(3,4,5-trimethoxybenzylidene)benzohydrazide
por: Xu, Liang, et al.
Publicado: (2009)

Triphenyl(3,4,5-trimethoxybenzyl)phosphonium chloride monohydrate
por: Barkell, Alice M., et al.
Publicado: (2008)

2-(3,4,5-Trimethoxyphenyl)-1H-benzimidazole
por: Khalaji, Aliakbar Dehno, et al.
Publicado: (2008)

4,4,5,5-Tetramethyl-2-(3,4,5-trimethoxyphenyl)imidazolidine-1-oxyl 3-oxide
por: Wang, Hai-Bo, et al.
Publicado: (2009)

3,4-Dimethoxy-4′-methylbiphenyl
por: Lahtinen, Manu, et al.
Publicado: (2013)

Pentafluorophenyl (3R,4R,5S)-5-{[(3R,4R,5S)-5-azidomethyl-3,4-dimethoxy-2,3,4,5-tetrahydrofuran-3-carboxamido]methyl}-3,4-dimethoxy-2,3,4,5-tetrahydrofuran-3-carboxylate
por: Simone, Michela I., et al.
Publicado: (2010)

Ethyl 4′-ethenyl-2′-oxo-4-phenyl-2-(3,4,5-trimethoxyphenyl)spiro[pyrrolidine-3,3′-indoline]-5-carboxylate monohydrate
por: Sathyanarayanan, M., et al.
Publicado: (2008)

4-(2-Methoxyphenyl)-3-(3,4,5-trimethoxyphenethyl)-2H-1,2,4-triazole-5(4H)-thione
por: Qadeer, Ghulam, et al.
Publicado: (2007)

N-(3,4-Difluorophenyl)-2-(3,4-dimethoxyphenyl)acetamide
por: Hong, Won Ki, et al.
Publicado: (2008)

(E)-Methyl N′-(3,4,5-trimethoxybenzylidene)hydrazinecarboxylate
por: Lv, Lu-Ping, et al.
Publicado: (2008)

(E)-Ethyl N′-(3,4,5-trimethoxybenzylidene)hydrazinecarboxylate
por: Lv, Lu-Ping, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_gv9t340rtumcpnam0lntlltn29