Synthesis of Bioactive 2-(Arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation

A library of thirty eight novel thiazolo[5,4-f]quinazolin-9(8H)-one derivatives (series 8, 10, 14 and 17) was prepared via the Hügershoff reaction and a Cu catalyzed intramolecular C-S bond formation, helped by microwave-assisted technology when required. The efficient multistep synthesis of the key...

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Detalles Bibliográficos
Autores principales: Hédou, Damien, Dubouilh-Benard, Carole, Loaëc, Nadège, Meijer, Laurent, Fruit, Corinne, Besson, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272913/
https://www.ncbi.nlm.nih.gov/pubmed/27322235
http://dx.doi.org/10.3390/molecules21060794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272913/
https://www.ncbi.nlm.nih.gov/pubmed/27322235
http://dx.doi.org/10.3390/molecules21060794

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