Efficient Synthesis of the Lewis A Tandem Repeat

The convergent synthesis of the Lewis A (Le(a)) tandem repeat is described. The Le(a) tandem repeat is a carbohydrate ligand for a mannose binding protein that shows potent inhibitory activity against carcinoma growth. The Le(a) unit, {β-d-Gal-(1→3)-[α-l-Fuc-(1→4)]-β-d-GlcNAc}, was synthesized by st...

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Detalles Bibliográficos
Autores principales: Kobayashi, Daisuke, Ueki, Akiharu, Yamaji, Tomoya, Nagao, Kazuya, Imamura, Akihiro, Ando, Hiromune, Kiso, Makoto, Ishida, Hideharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272916/
https://www.ncbi.nlm.nih.gov/pubmed/27187324
http://dx.doi.org/10.3390/molecules21050614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272916/
https://www.ncbi.nlm.nih.gov/pubmed/27187324
http://dx.doi.org/10.3390/molecules21050614

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