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Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats

Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, and Fructus Gardeniae are often used alongside with clozapine (CLZ) for schizophrenia patients in order to reduce side effects and enhance therapeutic efficacy. However, worse outcomes were observed raising concern about a critical issue, herb-d...

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Detalles Bibliográficos
Autores principales: Tian, Dan-Dan, Wang, Wei, Wang, Hua-Ning, Sze, Stephen Cho Wing, Zhang, Zhang-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272930/
https://www.ncbi.nlm.nih.gov/pubmed/27240333
http://dx.doi.org/10.3390/molecules21060696