In Vivo and in Vitro Study on Drug-Drug Interaction of Lovastatin and Berberine from Pharmacokinetic and HepG2 Cell Metabolism Studies

Background: We assumed that the pharmacokinetics of lovastatin could be changed by the induction effect of berberine. Methods: An UPLC-MS/MS method was developed and validated for the pharmacokinetics tudy of lovastatin to investigate the in vivo drug-drug interactions between lovastatin and berberi...

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Detalles Bibliográficos
Autores principales: Cui, Hanming, Wang, Jialong, Zhang, Qiuyan, Dang, Mengmeng, Liu, Hui, Dong, Yu, Zhang, Lu, Yang, Fang, Wu, Jianhua, Tong, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272956/
https://www.ncbi.nlm.nih.gov/pubmed/27070564
http://dx.doi.org/10.3390/molecules21040464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272956/
https://www.ncbi.nlm.nih.gov/pubmed/27070564
http://dx.doi.org/10.3390/molecules21040464

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