Synthesis, Antiphospholipase A(2), Antiprotease, Antibacterial Evaluation and Molecular Docking Analysis of Certain Novel Hydrazones

Some novel hydrazone derivatives 6a–o were synthesized from the key intermediate 4-Chloro-N-(2-hydrazinocarbonyl-phenyl)-benzamide 5 and characterized using IR, (1)H-NMR, (13)C-NMR, mass spectroscopy and elemental analysis. The inhibitory potential against two secretory phospholipase A(2) (sPLA(2)),...

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Detalles Bibliográficos
Autores principales: El-Sayed, Nahed N. E., Alafeefy, Ahmed M., Bakht, Mohammed A., Masand, Vijay H., Aldalbahi, Ali, Chen, Nan, Fan, Chunhai, Ben Bacha, Abir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272960/
https://www.ncbi.nlm.nih.gov/pubmed/27918459
http://dx.doi.org/10.3390/molecules21121664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272960/
https://www.ncbi.nlm.nih.gov/pubmed/27918459
http://dx.doi.org/10.3390/molecules21121664

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