Self Organizing Map-Based Classification of Cathepsin k and S Inhibitors with Different Selectivity Profiles Using Different Structural Molecular Fingerprints: Design and Application for Discovery of Novel Hits

The main step in a successful drug discovery pipeline is the identification of small potent compounds that selectively bind to the target of interest with high affinity. However, there is still a shortage of efficient and accurate computational methods with powerful capability to study and hence pre...

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Detalles Bibliográficos
Autores principales: Ihmaid, Saleh K., Ahmed, Hany E. A., Zayed, Mohamed F., Abadleh, Mohammed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272978/
https://www.ncbi.nlm.nih.gov/pubmed/26840291
http://dx.doi.org/10.3390/molecules21020175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272978/
https://www.ncbi.nlm.nih.gov/pubmed/26840291
http://dx.doi.org/10.3390/molecules21020175

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