A Selective Cyclic Peptidic Human SIRT5 Inhibitor

In the current study, we discovered that a side chain-to-side chain cyclic pentapeptide harboring a central N(ε)-carboxyethyl-thiocarbamoyl-lysine residue behaved as a strong and selective (versus human SIRT1/2/3/6) inhibitor against human SIRT5-catalyzed deacylation reaction. This compound was also...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jiajia, Huang, Yajun, Zheng, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272981/
https://www.ncbi.nlm.nih.gov/pubmed/27626398
http://dx.doi.org/10.3390/molecules21091217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272981/
https://www.ncbi.nlm.nih.gov/pubmed/27626398
http://dx.doi.org/10.3390/molecules21091217

Ejemplares similares