Preparation and Biological Evaluation of Two Novel Platinum(II) Complexes Based on the Ligands of Dipicolyamine Bisphosphonate Esters

Two new platinum(II)-based complexes bearing a bone-targeting group were synthesized and characterized. They both have excellent affinity for hydroxyapatite (HA), which is abundant in human bone tissues. Their antitumor activities against five human cancer cell lines (U2OS, A549, HCT116, MDA-MB-231...

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Detalles Bibliográficos
Autores principales: Qiu, Ling, Liu, Hong, Li, Ke, Lv, Gaochao, Yang, Hui, Qin, Xiaofeng, Lin, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272982/
https://www.ncbi.nlm.nih.gov/pubmed/26927037
http://dx.doi.org/10.3390/molecules21030255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272982/
https://www.ncbi.nlm.nih.gov/pubmed/26927037
http://dx.doi.org/10.3390/molecules21030255

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