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Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes

Incubation systems were established to investigate the effects of quercetin, kaempferol, isoquercitrin and astragalin in Lysimachia clethroides Duby on the activities of CYP2E1 and CYP3A4 in rat liver microsomes in vitro. Probe substrates of 4-nitrophenol and testosterone as well as flavonoids at di...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi-Juan, Xia, Zhao-Yang, Wang, Jin-Mei, Song, Xue-Ting, Wei, Jin-Feng, Kang, Wen-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273018/
https://www.ncbi.nlm.nih.gov/pubmed/27314315
http://dx.doi.org/10.3390/molecules21060738