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Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine

The use of small interference RNA (siRNA) to target oncogenes is a promising treatment approach for cancer. However, siRNA cancer therapies are hindered by poor delivery of siRNA to cancer cells. Transferrin receptor (TfR) is overexpressed in many types of tumor cells and therefore is a potential ta...

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Detalles Bibliográficos
Autores principales: Xie, Yuran, Killinger, Bryan, Moszczynska, Anna, Merkel, Olivia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273023/
https://www.ncbi.nlm.nih.gov/pubmed/27735873
http://dx.doi.org/10.3390/molecules21101334