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Biocatalytic Synthesis of Novel Partial Esters of a Bioactive Dihydroxy 4-Methylcoumarin by Rhizopus oryzae Lipase (ROL)

Highly regioselective acylation has been observed in 7,8-dihydroxy-4-methylcoumarin (DHMC) by the lipase from Rhizopus oryzae suspended in tetrahydrofuran (THF) at 45 °C using six different acid anhydrides as acylating agents. The acylation occurred regioselectively at one of the two hydroxy groups...

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Detalles Bibliográficos
Autores principales: Kumar, Vinod, Mathur, Divya, Srivastava, Smriti, Malhotra, Shashwat, Rana, Neha, Singh, Suraj K., Singh, Brajendra K., Prasad, Ashok K., Varma, Anjani J., Len, Christophe, Kuhad, Ramesh C., Saxena, Rajendra K., Parmar, Virinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273029/
https://www.ncbi.nlm.nih.gov/pubmed/27834873
http://dx.doi.org/10.3390/molecules21111499