DeBouganin Diabody Fusion Protein Overcomes Drug Resistance to ADCs Comprised of Anti-Microtubule Agents

Antibody drug conjugates (ADC), comprised of highly potent small molecule payloads chemically conjugated to a full-length antibody, represent a growing class of therapeutic agents. The targeting of cytotoxic payloads via the specificity and selectivity of the antibody has led to substantial clinical...

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Detalles Bibliográficos
Autores principales: Chooniedass, Shilpa, Dillon, Rachelle L., Premsukh, Arjune, Hudson, Peter J., Adams, Gregory P., MacDonald, Glen C., Cizeau, Jeannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273041/
https://www.ncbi.nlm.nih.gov/pubmed/27999336
http://dx.doi.org/10.3390/molecules21121741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273041/
https://www.ncbi.nlm.nih.gov/pubmed/27999336
http://dx.doi.org/10.3390/molecules21121741

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