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The Alterations in the Expression and Function of P-Glycoprotein in Vitamin A-Deficient Rats as well as the Effect of Drug Disposition in Vivo

This study was aimed to investigate whether vitamin A deficiency could alter P-GP expression and function in tissues of rats and whether such effects affected the drug distribution in vivo of vitamin A-deficient rats. We induced vitamin A-deficient rats by giving them a vitamin A-free diet for 12 we...

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Detalles Bibliográficos
Autores principales: Wang, Yubang, Qin, Heng, Zhang, Chengxiang, Huan, Fei, Yan, Ting, Zhang, Lulu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273054/
https://www.ncbi.nlm.nih.gov/pubmed/26729079
http://dx.doi.org/10.3390/molecules21010046