Identification of a New Morpholine Scaffold as a P2Y12 Receptor Antagonist

The P2Y12 receptor is critical for platelet activation and is an attractive drug target for the prevention of atherothrombotic events. Despite the proven antithrombotic efficacy of P2Y12 inhibitors, these thienopyridine scaffolds are prodrugs that lack important features of the ideal antithrombotic...

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Detalles Bibliográficos
Autores principales: Ahn, Young Ha, Lee, Joo-Youn, Park, Hee Dong, Kim, Tae Hun, Park, Min Chul, Choi, Gildon, Kim, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273072/
https://www.ncbi.nlm.nih.gov/pubmed/27563870
http://dx.doi.org/10.3390/molecules21091114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273072/
https://www.ncbi.nlm.nih.gov/pubmed/27563870
http://dx.doi.org/10.3390/molecules21091114

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