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Synthesis of Chlorinated Tetracyclic Compounds and Testing for Their Potential Antidepressant Effect in Mice

The synthesis of the tetracyclic compounds 1-(4,5-dichloro-9,10-dihydro-9,10-ethanoanthracen-11-yl)-N-methylmethanamine (5) and 1-(1,8-dichloro-9,10-dihydro-9,10-ethanoanthracen-11-yl)-N-methylmethanamine (6) as a homologue of the anxiolytic and antidepressant drugs benzoctamine and maprotiline were...

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Detalles Bibliográficos
Autores principales: Karama, Usama, Sultan, Mujeeb A., Almansour, Abdulrahman I., El-Taher, Kamal Eldin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273077/
https://www.ncbi.nlm.nih.gov/pubmed/26742028
http://dx.doi.org/10.3390/molecules21010061