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A Potential Mechanism for the Anti-Apoptotic Property of Koumine Involving Mitochondrial Pathway in LPS-Mediated RAW 264.7 Macrophages

Koumine is a kind of alkaloid extracted from Gelsemium elegans (G. elegans). Benth, which has shown promise as an anti-tumor, anxiolytic, and analgesic agent. In our present study, the effect of koumine on lipopolysaccharide (LPS)-mediated RAW 264.7 cell apoptosis was evaluated. MTT assays showed th...

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Detalles Bibliográficos
Autores principales: Yuan, Zhi-Hang, Liang, Zeng-Enni, Wu, Jing, Yi, Jin-E, Chen, Xiao-Jun, Sun, Zhi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273091/
https://www.ncbi.nlm.nih.gov/pubmed/27706063
http://dx.doi.org/10.3390/molecules21101317