Synthesis and In Vitro Antiproliferative Activity of Novel Phenyl Ring-Substituted 5-Alkyl-12(H)-quino[3,4-b][1,4]benzothiazine Derivatives

A novel series of tetracyclic quinobenzothiazine derivatives was synthetized. Compounds containing a substituent (hydroxyl, methyl, phenyl, piperidyl, or piperazinyl) in positions 9 and 11 were obtained by cyclization of suitable 4-aminoquinolinium-3-thiolates. Quinobenzothiazine 10-O-substituted de...

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Detalles Bibliográficos
Autores principales: Zięba, Andrzej, Latocha, Małgorzata, Sochanik, Aleksander, Nycz, Anna, Kuśmierz, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273095/
https://www.ncbi.nlm.nih.gov/pubmed/27827930
http://dx.doi.org/10.3390/molecules21111455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273095/
https://www.ncbi.nlm.nih.gov/pubmed/27827930
http://dx.doi.org/10.3390/molecules21111455

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