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Role of Intestinal Microbiota in Baicalin-Induced Drug Interaction and Its Pharmacokinetics

Since many glycoside compounds in natural products are hydrolyzed by intestinal microbiota when administered orally, it is of interest to know whether their pharmacological effects are derived from the glycoside itself or from the aglycone form in vivo. An interesting example is baicalin versus baic...

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Detalles Bibliográficos
Autores principales: Noh, Keumhan, Kang, Youra, Nepal, Mahesh Raj, Jeong, Ki Sun, Oh, Do Gyeong, Kang, Mi Jeong, Lee, Sangkyu, Kang, Wonku, Jeong, Hye Gwang, Jeong, Tae Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273104/
https://www.ncbi.nlm.nih.gov/pubmed/26978333
http://dx.doi.org/10.3390/molecules21030337