Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5′-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

Aschantin is a bioactive neolignan found in Magnolia flos with antiplasmodial, Ca(2+)-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities. We investigated its inhibitory effects on the activities of eight major human cytochrome P450 (CYP) and uridine 5′-diphospho-gl...

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Detalles Bibliográficos
Autores principales: Kwon, Soon-Sang, Kim, Ju-Hyun, Jeong, Hyeon-Uk, Cho, Yong Yeon, Oh, Sei-Ryang, Lee, Hye Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273138/
https://www.ncbi.nlm.nih.gov/pubmed/27128896
http://dx.doi.org/10.3390/molecules21050554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273138/
https://www.ncbi.nlm.nih.gov/pubmed/27128896
http://dx.doi.org/10.3390/molecules21050554

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