Direct Separation of Pregabalin Enantiomers Using a Zwitterionic Chiral Selector by High Performance Liquid Chromatography Coupled to Mass Spectrometry and Ultraviolet Detection

The chromatographic resolution of pregabalin enantiomers has been often achieved by derivatization of the molecule, in order to reach enough sensitivity at low concentrations of the minor enantiomer present in the active principle. In the present article, the development and optimization of two liqu...

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Detalles Bibliográficos
Autores principales: Chennuru, Lakshmi Narayana, Choppari, Thirupathi, Nandula, Ramakrishna Prasad, Zhang, Tong, Franco, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273170/
https://www.ncbi.nlm.nih.gov/pubmed/27869770
http://dx.doi.org/10.3390/molecules21111578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273170/
https://www.ncbi.nlm.nih.gov/pubmed/27869770
http://dx.doi.org/10.3390/molecules21111578

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