Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures

The regulation of thrombin activity offers an opportunity to regulate blood clotting because of the central role played by this molecule in the coagulation cascade. Thrombin-binding DNA aptamers have been used to inhibit thrombin activity. In the past, to address the low efficacy reported for these...

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Detalles Bibliográficos
Autores principales: Rangnekar, Abhijit, Nash, Jessica A., Goodfred, Bethany, Yingling, Yaroslava G., LaBean, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273181/
https://www.ncbi.nlm.nih.gov/pubmed/26861277
http://dx.doi.org/10.3390/molecules21020202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273181/
https://www.ncbi.nlm.nih.gov/pubmed/26861277
http://dx.doi.org/10.3390/molecules21020202

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